What is it about?
This study uses a combination of a multi-channel conduit, essentially a tube with multiple lumens, and gene therapy to improve recovery from a spinal cord injury. Here a non-viral delivery methods is used to increase the production of neurotrophin-3 in the surrounding cells of the injured cord. Neurotrophin-3 is growth factor/molecule which has been shown to increase the number of regenerating axons in the cord and to promote their survival during regeneration.
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This page is a summary of: Improved axonal regeneration of transected spinal cord mediated by multichannel collagen conduits functionalized with neurotrophin-3 gene, Gene Therapy, July 2013, Springer Science + Business Media,
DOI: 10.1038/gt.2013.42.
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