Publication
Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains
Olivier Mirguet, Romain Gosmini, Jérôme Toum, Catherine A. Clément, Mélanie Barnathan, Jean-Marie Brusq, Jacqueline E. Mordaunt, Richard M. Grimes, Miriam Crowe, Olivier Pineau, Myriam Ajakane, Alain Daugan, Phillip Jeffrey, Leanne Cutler, Andrea C. Haynes, Nicholas N. Smithers, Chun-wa Chung, Paul Bamborough, Iain J. Uings, Antonia Lewis, Jason Witherington, Nigel Parr, Rab K. Prinjha, Edwige Nicodème
Journal of Medicinal Chemistry, October 2013, American Chemical Society (ACS)
DOI: 10.1021/jm401088k