What is it about?
dose response effects of EGF & GDNF on synchronization of nuclear and cytoplasmic maturation of porcine oocytes
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Why is it important?
Compared with the embryos obtained from control or single growth factor-treated oocytes, treatment with the combination of EGF and GDNF was shown to significantly improve oocyte competence in terms of blastocyst formation, blastocyst cell number and blastocyst hatching rate (P < 0.05), and also simultaneously induced the expression of BCL-xL and TERT and suppressed the expression of caspase-3 in resulting blastocysts (P < 0.05)
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This page is a summary of: Combination effects of epidermal growth factor and glial cell line-derived neurotrophic factor on the in vitro developmental potential of porcine oocytes, Zygote, September 2015, Cambridge University Press,
DOI: 10.1017/s0967199415000416.
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