What is it about?
It is a meta-analysis examining the effect of cerebral microbleeds on neuropsychological performance in Alzheimer's disease patients. We have shown that neuroimaging factors and how microbleeds are defined can affect neuropsychological outcomes and group placement in trials/studies, with a subsequent effect on observing and effect on global neurocognitive performance.
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Why is it important?
It is important because A) it could affect future studies and patient placement for clinical trials/ and comparative studies; B) shows the effect of microbleeds in Alzheimer's patients, that otherwise was perceived as bystanders.
Perspectives
In future studies, or at clinical settings, clinicians would be more careful with dealing with Alzheimer's patients presenting with microbleeds and take that into consideration when looking at neuropsychological performance. This study should help experts plan for neuropsychological studies of microbleeds that are well defined and examined by neuroimaging tools.
Dr. Amir A Sepehry
University of Brtish Columbia
Read the Original
This page is a summary of: Microbleeds in Alzheimer’s Disease: A Neuropsychological Overview and Meta-Analysis, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, September 2016, Cambridge University Press,
DOI: 10.1017/cjn.2016.296.
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