What is it about?

The causes of high anion gap metabolic acidosis (HAGMA) are well described in the literature. However, sometimes more frequent causes of HAGMA cannot explain its occurrence. In the case of HAGMA and severe neurological depression in the absence of other causes of HAGMA, clinicians should consider an intoxication with gamma-hydroxybutyrate (GHB) as a possible cause.

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Why is it important?

The causes of high anion gap metabolic acidosis (HAGMA) are well described in the literature. However, sometimes more frequent causes of HAGMA cannot explain its occurrence.

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This page is a summary of: Gamma-hydroxybutyrate (GHB), an unusual cause of high anion gap metabolic acidosis, Canadian Journal of Emergency Medicine, May 2017, Cambridge University Press,
DOI: 10.1017/cem.2017.10.
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