What is it about?

This article provides a concise overview of the major receptors involved in platelet adhesion to collagen, the first step towards formation of a platelet plug to seal off a wound. For each receptor, a description of the molecular structure, the collagen recognition sequence and its specific role in platelet adhesion are given.

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Why is it important?

This review summarizes the current knowledge on the individual roles and structure–function relationships of the main platelet adhesion receptors. It provides a good starting point for researchers who want to know more about platelet adhesion, the first step towards formation of a platelet plug to seal off a wound

Perspectives

This review is among the better in its kind, because it delivers a good and concise overview in just 4 pages, making it an ideal starting point for further reading.

Dr. Tim Thijs
Katholieke Universiteit Leuven

Read the Original

This page is a summary of: Platelet adhesion to collagen, Thrombosis Research, January 2011, Elsevier,
DOI: 10.1016/s0049-3848(10)70151-1.
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