What is it about?
FXR activated by bile acids repress apoC3 expression and thus lowers plasma triglycerides levels
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Why is it important?
FXR agonists could help hyper triglyceridemic patients
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This page is a summary of: Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression, Gastroenterology, August 2003, Elsevier,
DOI: 10.1016/s0016-5085(03)00896-5.
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