What is it about?
Mathematical analysis of the kinetics of receptor binding that lead to biological effects (ergokinetics)
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Why is it important?
The Druckrey-Küpfmüller theorem has been shown to be universally applicable and explains the dose-response characteristics of chemical carcinogens and other hazardous chemicals.
Perspectives
Application of the Druckrey-Kúpfmüller theorem in regulatory toxicology can lead to early hazard identification and simplification of product development, and a reduction of animal experimentation.
Dr Henk A. Tennekes
Experimental Toxicology Services (ETS) Nederland BV
Read the Original
This page is a summary of: The molecular basis of simple relationships between exposure concentration and toxic effects with time, Toxicology, July 2013, Elsevier,
DOI: 10.1016/j.tox.2013.04.007.
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