What is it about?
A persistent epithelial defect (PED) is a corneal epithelial flaw that failed to heal after 2 weeks. It is a condition that brings much mortality, and our knowledge of PED remains poor, with present treatment ways often having bad results. With PEDs becoming more common, more efforts are needed to create effective treatment methods. Our reviews describe the reasons of PEDs and the different methods created to handle them, as well as their related limits. Emphasis is put on learning different breakthroughs in the creation of new treatment methods. We have also reported a case of a woman with a past of graft-versus-host disease on long-term external prednisone who got complex PED involving both eyes. The current method to treating PEDs usually involves removal of an active infection, followed by treatment options that aim to encourage eye epithelium repair. Success rates, however, remain far from ideal, as treatment remains difficult due to multiple underlying etiologies. In summary, improvements in the creation of new medicines may be able to aid growth in the study and treatment of PED.
Featured Image
Photo by National Cancer Institute on Unsplash
Why is it important?
There are no easy way to treat a defect on the cornea
Perspectives
Treatment corneal defect improves vision and prevents devastating infections
Prof Louis Tong
National University of Singapore
Read the Original
This page is a summary of: New developments in the management of persistent corneal epithelial defects, Survey of Ophthalmology, June 2023, Elsevier,
DOI: 10.1016/j.survophthal.2023.06.001.
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