What is it about?
Xhantine Dehydrogenase (XDH) is highly expressed in nodules from P. vulgaris and it is regulated at transcriptional and posttranscriptional levels under stress conditions. The enzyme is inhibited by nitric oxide, released by SNP, in vitro. Silencing of PvXDH RNAi revealed that the enzyme is protected from NO in nodules by the high levels of its reaction product, uric acid.
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Why is it important?
Because uric acid has to be considered among the protective batery of compounds acting against nitrosidative stress in nodules of ureidic legumes.
Perspectives
I find it would be important to highlight that nodules of ureide producing legumes bear strong functional differences with amide legumes.
Dr Josefa M. Alamillo
University of Cordoba
Read the Original
This page is a summary of: Molecular and biochemical analysis of XDH from Phaseolus vulgaris suggest that uric acid protects the enzyme against the inhibitory effects of nitric oxide in nodules, Plant Physiology and Biochemistry, October 2019, Elsevier,
DOI: 10.1016/j.plaphy.2019.09.008.
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