What is it about?
This is the first study that provides a quantitative correlation between single cell mechanics and loss of cell adhesion in the progression of diseases (e.g. diabetics) using single-cell AFM force spectroscopy.
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Why is it important?
The technique can detect the subtle changes in cell elasticity, cell-to-cell adhesion force and energy etc. in the progression of diseases.
Perspectives
It has the potential for developing new single-cell-based techniques for disease detection.
Dr Isaac LIU
University of Warwick
Read the Original
This page is a summary of: Quantifying cellular mechanics and adhesion in renal tubular injury using single cell force spectroscopy, Nanomedicine Nanotechnology Biology and Medicine, May 2016, Elsevier,
DOI: 10.1016/j.nano.2015.12.362.
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