What is it about?
The DNA is a circular molecule of 109 103 base pairs, with 31.9 % GC, and is the largest sequenced so far. This size is due essentially to the presence of numerous non-conserved hypothetical ORFs. It contains the 14 genes coding for proteins involved in the oxidative phosphorylation, the two rRNA genes, one ORF coding for a ribosomal protein (rps3), and a set of 26 tRNA genes that recognize codons for all amino acids. Seven homing endonucleases are located inside introns. Except atp8, all conserved known genes are in the same orientation. Phylogenetic analysis based on the cox genes agrees with the commonly accepted fungal taxonomy.
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Why is it important?
Moniliophthora perniciosa is the fungal agent that causes the witches' broom disease of cocoa, a disease that devastates the cocoa production in Brazil.
Perspectives
This project was part of an iniciative dedicated to the full genome sequencing with the purpose of helping Brazilian research to control this disease.
Nicolas Carels
Oswaldo Cruz Foundation
Read the Original
This page is a summary of: The mitochondrial genome of the phytopathogenic basidiomycete Moniliophthora perniciosa is 109kb in size and contains a stable integrated plasmid, Mycological Research, October 2008, Elsevier,
DOI: 10.1016/j.mycres.2008.04.014.
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