What is it about?
Bioactive glass with the composition 0.55SiO2·0.41CaO·0.04P2O5 was prepared following the sol–gel route as controlled delivery systems for tetracycline (TC).
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Why is it important?
The obtained results demonstrate that the pores size modification related to different maturation and drying procedures seems to be a determinative factor in tetracycline release process.
Perspectives
The maturation and drying of the gel under different conditions led to different behavior regarding the loading and release of TC from these matrices. The pore size modifications upon TC loading evidenced by BET method show different ability of the glass matrices with respect to TC incorporation, also supported by experimental EPR and fluorescence spectroscopy.
Professor Simona Cavalu
University of Oradea
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This page is a summary of: Microscopic and spectroscopic investigation of bioactive glasses for antibiotic controlled release, Journal of Molecular Structure, May 2013, Elsevier,
DOI: 10.1016/j.molstruc.2013.02.016.
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