What is it about?
The quality of vision depends largely on clarity of the cornea. Even after successful elimination of infection the visual rehabilitation is often poor because of residual stromal scarring. This article will help you understand the evolution of corneal scar and thus throw some light upon its pathogenesis and possible future treatment remedies.
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Why is it important?
The study of evolution of surgically induced scars in controlled animal models would help us identify and thus target the potential triggers to achieve a desirable outcome. This will also help us to explore the role of newer regenerative therapies such as mesenchymal stem cell transplant, gene therapy and biological adhesives.
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This page is a summary of: A reliable animal model of corneal stromal opacity: Development and validation using in vivo imaging, The Ocular Surface, July 2020, Elsevier,
DOI: 10.1016/j.jtos.2020.07.017.
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