What is it about?

We monitor patients before and after glaucoma surgery, and collect tears at different time points to assay for inflammatory lipids.

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Why is it important?

Lipid mediators cause inflammation and redness and potentially fibrosis in the ocular surface. Fibrosis leads to failure of the surgery and potentially irreversible blindness. If the levels of these mediators decrease after surgery, the chances of surgical success are improved.

Perspectives

Trabeculectomy is still the gold standard surgery for glaucoma. However, the effect of such surgery, compared to long term use of glaucoma medications, on the ocular surface, is relatively unknown.

Prof Louis Tong
National University of Singapore

Read the Original

This page is a summary of: Change of tear lipid mediators in a post-trabeculectomy cohort, The Ocular Surface, October 2020, Elsevier,
DOI: 10.1016/j.jtos.2020.06.004.
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