What is it about?

Highlights • This review demonstrated that OSA increased risk of postoperative cardiac complications in non-cardiac surgery. • Thus, it is crucial to identify surgical patients at risk of OSA and be monitored closely after surgery. • The level of evidence ranged from very low to low due to risk of bias, inconsistency and publication bias.

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Why is it important?

We hypothesized that OSA increased the risk of postoperative cardiac or cerebrovascular complications in non-cardiac surgery. The primary aim of this systematic review was to examine the association of OSA and the composite endpoints of postoperative cardiac or cerebrovascular complications in adult patients undergoing non-cardiac surgery. Secondary aims were to investigate other postoperative outcomes of OSA patients when compared to non-OSA, namely incidence of composite endpoints of postoperative pulmonary complications, in-hospital mortality, 30-day mortality, acute kidney injury, postoperative delirium, cerebrovascular accident, venoembolism, reintubation, surgical site infection, unplanned intensive care unit (ICU) admission, postoperative bleeding, cost of hospitalization (dollars) and length of hospital stays (days).

Perspectives

This meta-analysis of 22 comparative studies demonstrated that OSA is a potential risk factor to postoperative adverse complications in adults undergoing non-cardiac surgery. However, the conclusions need to be interpreted with caution due to the nature of included observational studies with significant heterogeneity and low quality of evidence.

Dr Ka Ting Ng
University of Malaya

Read the Original

This page is a summary of: Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis, Journal of Clinical Anesthesia, June 2020, Elsevier,
DOI: 10.1016/j.jclinane.2020.109731.
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