What is it about?
This work presents attachment of drugs to nanomaterials for targetting cancerous zone by nanomedicine
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Why is it important?
It explores various types of nanoparticles and their surface/chemical modifications as well as attachment of targeting ligands for tuning their properties in order to facilitate targeted delivery to the cancer sites in a rate-controlled manner.
Perspectives
Heme compatibility, biodistribution, longer circulation time, hydrophilic lipophilic balance for high bioavailability, prevention of drug degradation and leakage are important in transporting drugs to the targeted cancer sites. The review discusses advantages of polymeric, magnetic, gold, and mesoporous silica NPs in delivering chemotherapeutic agents over the conventional dosage formulations along with their shortcomings/risks and possible solutions/alternatives.
Dr Afzal Shah
Quaid-i-Azam University, Iislamabad
Read the Original
This page is a summary of: Nanomedicine: An effective tool in cancer therapy, International Journal of Pharmaceutics, April 2018, Elsevier,
DOI: 10.1016/j.ijpharm.2018.02.007.
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