What is it about?
Unlike Mycobacterium tuberculosis which has only Type II flavohemoglobin, Mycobacterium smegmatis possesses both Type I and Type II flavohemoglobin. Here we have characterised the Type II flavohemoglobin of Mycobacterium smegmatis. It is very similar to its homologue in Mycobacterium tuberculosis and uses d-lactate as an electron donor and its heme as an electron acceptor. Identification of ultimate substrate of Type II flavohemoglobins will be another major contribution.
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Why is it important?
It defines spectral characteristics of Type II flavohemoglobin.
Perspectives
This and few other studies are milestones in our understanding of different types of flavohemoglobins.
Ashwani Kumar
CSIR-Institute of Microbial Technology, Chandigarh, India
Read the Original
This page is a summary of: Type II flavohemoglobin of Mycobacterium smegmatis oxidizes d-lactate and mediate electron transfer, International Journal of Biological Macromolecules, June 2018, Elsevier,
DOI: 10.1016/j.ijbiomac.2018.02.010.
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