A review of flow and aerosol measurements in human airways

What is it about?

In silico methods are emerging as an important route for the determination of regional deposition of drug particles in the lungs. Even though such computational tools help overcome some of the traditional limitations of in vivo (e.g. patient exposure to radiation) and in vitro methods (cost and time), they must rely on experimental methods for validation and verification and the specification of boundary/input conditions. In this paper we provide a thorough review of the current status of various experimental methods that can be used for the measurement of the flowfield and of aerosol deposition in the human lungs.

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Why is it important?

This review manuscript should provide a concise but thorough view of the tools that are available for the quantification of the air flow and aerosol deposition in the human lungs. Should of interest to both experimentalists and computational scientists.

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