What is it about?

Discovering new drugs is a risky, expensive and time-consuming business. One way organisations are looking to spread the risk is to work together in Open Innovation partnerships. We define open innovation thus: “The process of innovating with others for shared risk and reward to produce mutual benefits for each organisation, creating new products, processes or ideas that could not otherwise have been achieved alone, or enabling them to be achieved more quickly, cheaply or efficiently". This way of working can cause problems for the managers of research organisations' compound collections. We describe a potential solution.

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Why is it important?

The trend towards open innovation means researchers face new problems tracking assets. We borrow from social media concepts to solve these problems. A SOA service is described that provides support and clarity to asset owners. The accurate capture of metadata allows accurate asset rights management.

Perspectives

More early discovery collaborative agreements are being put in place between large pharma companies and partners in which the rights for assets may reside with a partner, exclusively or jointly. Our corporate screening collection, like many others was built on the premise that compounds generated in-house and not the subject of paper or patent disclosure were proprietary to the company. Collaborative screening arrangements and medicinal chemistry now make the origin, ownership rights and usage of compounds difficult to determine and manage. The Compound Passport Service is a dynamic database, managed and accessed through a set of reusable services that borrows from social media concepts to allow sample owners to take control of their samples in a much more active way.

Dr David M Andrews
AstraZeneca Pharmaceutical Co Ltd

Read the Original

This page is a summary of: Compound Passport Service: supporting corporate collection owners in open innovation, Drug Discovery Today, October 2015, Elsevier,
DOI: 10.1016/j.drudis.2015.06.011.
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