Vitamin D in Crohn's disease

What is it about?

We showed that vitamin D deficiency was common in patients with an autoimmune disease of the gut, known as Crohn’s disease (CD). Deficiency was more likely in patients with long-standing disease and in those who smoked. This has important implications for bone health in CD, and potentially for other health outcomes.

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Why is it important?

We confirmed that vitamin D deficiency is common even in patients in Crohn’s disease (CD) in remission. Newer studies, today, now suggest that low vitamin D status in this disease may be associated with more severe inflammation. Potentially, correcting deficiency or raising blood levels of vitamin D might have anti-inflammatory effects. This newer area for vitamin D in inflammation in CD is interesting, but remains controversial and further work is needed to confirm.