What is it about?
Molecular simulation of the permeation of the peptide human beta-defensin-3 in two different lung surfactant models.
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Why is it important?
Some lung surfactant seems to have less or none electrostatic interaction with human beta-defensin-3, possibly preserving its antimicrobial activity.
Perspectives
It is important to perform in vitro and in vivo tests with human beta-defensin-3 encapsulated with PEG polymer.
Dr Andre S Pimentel
Pontificia Universidade Catolica do Rio de Janeiro
Read the Original
This page is a summary of: Permeation of beta-defensin-3 encapsulated with polyethylene glycol in lung surfactant models at air-water interface, Colloids and Surfaces B Biointerfaces, July 2019, Elsevier,
DOI: 10.1016/j.colsurfb.2019.110357.
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