What is it about?

In this review, we will investigate the phenotype, generation, and role of these cells, concentrating on their production of cytokines, plasticity and on their interactions with other immune cells in the tumor milieu. As a final point, we consider the clinical correlation of Th17 cells in tumor immunology and underline their therapeutic potential.

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Perspectives

A comprehensive approach to indicating the activity of Th17 cells in tumor progression could help in the planning of new therapeutic approaches especially targeting Th17 cells in cancer.

Hamed Mohammadi

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This page is a summary of: The paradox of Th17 cell functions in tumor immunity, Cellular Immunology, December 2017, Elsevier,
DOI: 10.1016/j.cellimm.2017.10.015.
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