Cellulose acetate electrospun nanofibers for drug delivery systems

What is it about?

Today, nanofiber manufacturing acts as one of the remarkable breakthroughs of nanotechnology. The naturally high surface to volume proportion of nanofibers can improve drug incorporation and mass transport properties. The greenest available polymeric material, cellulose, possesses remarkable consumption of electrospun nanofibers. Cellulose composed of β(1→4) linked b-D-glucose units has notably considered due to its outstanding properties including (i) biodegradability and biocompatibility, (ii) abundant availability of a renewable resource, (iii) scalability and profitability

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Why is it important?

The biomedical applications of cellulose encounter the numerous obstacles including limited solubility in general organic solvent and its disability to melt due to extra inter-and intra-molecular hydrogen bonding. In this context, based on the current evidence, we could consider therapeutic agents of electrospun nanofibers and their applications in several different systems including; transdermal delivery systems, wound dressings, implants, postsurgical devices and also tissue engineering scaffolds.

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