Oncomirs and breast cancer

What is it about?

In this review, we discussed the role of various microRNAs that called oncomiRs and their role in the pathogenesis and treatment of breast cancer.

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Why is it important?

Some miRNAs, known as oncomiR, show different expression levels in cancer and are capable to effect on cellular transformation, carcinogenesis, and metastasis and are characterized by high expression levels in tumors compared to normal tissues. Therefore, oncomiRs can be considered as prognostic biomarkers and therapeutic targets in different types of cancers. Moreover, the utilization of oncomiRs as therapeutic targets for cancer is promising. Accordingly, there is evidence which implies an important role of various oncogenic microRNAs in the immunopathogenesis of breast cancer.