Protein-protein interactions involving enzymes of the mammalian methionine and homocysteine metabolism

What is it about?

This article is a review that summarizes the knowledge about protein-protein interactions involving enzymes of the methionine cycle and trans-sulfuration pathway. The interaction targets are described, as wel as the regulatory role of the interaction, whenever this is known. Moreover, the review introduces the reader into aspects that remain unanswered in the field and provides a view of the relationships of these pathways of intermediate metabolism with additional routes or reglatory mechanisms (e.g. glycolysis, splicing, etc.).

Featured Image

Why is it important?

The article provides information of the network of interactions of proteins in the methionine and homocysteine metabolism, expanding the actual knowledge about the involvement of enzymes of these pathways in additional routes, macromolecular complexes or regulatory mechanisms.

Perspectives