What is it about?
PAK1 overexpression and activation in inflammation and colitis-associated cancer promote NF-κB activity via suppression of PPARγ in intestinal epithelial cells
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Why is it important?
PPAR gamma agonist could help to fight intestinal inflammation when PAK1 is over activated
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This page is a summary of: PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2015, Elsevier,
DOI: 10.1016/j.bbamcr.2015.05.031.
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