Mesenchymal stem cell-based therapies for soft tissue reinforcement.

What is it about?

This review aims to summarize in vitro and in vivo studies involving the use of differentiated and mesenchymal stem cells in combination with surgical meshes. According to preclinical and clinical studies and considering the therapeutic potential of mesenchymal stem cells, it is expected that these cells will become valuable tools in the treatment of pathologies requiring tissue reinforcement.

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Why is it important?

Both differentiated cell- and stem cell-based therapies have become attractive tools to improve biocompatibility and tissue integration, minimizing adverse inflammatory reactions. This review aims to summarize in vitro and in vivo studies where differentiated and stem cells have been combined with surgical meshes.