What is it about?

We compared the morphological characteristics of muscle regeneration following cardiotoxin (CTX) and glycerol with special references to the structural changes of the intramuscular connective tissue (IMCT) during the regeneration process, by scanning electron microscopy (SEM) after digestion of the cellular elements of the muscle with sodium hydroxide.

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Why is it important?

Changes in IMCT affect the efficiency of muscle regeneration. Studying the three-dimensional structure of IMCT may help clinical therapies to reduce skeletal muscle fibrosis.

Perspectives

There is a significant difference during the process of degeneration and regeneration between CTX-injured muscle and the glycerol-injured one. It seems that changes in IMCT have a great impact on muscle regeneration.

Dr Mohamed A. A. Mahdy
South Valley University

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This page is a summary of: Comparative study of muscle regeneration following cardiotoxin and glycerol injury, Annals of Anatomy - Anatomischer Anzeiger, November 2015, Elsevier,
DOI: 10.1016/j.aanat.2015.07.002.
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