What is it about?
Sequence comparisons established the relatedness of several amino acid dehydrogenases. The existence of a solved structure for GluDH made it possible to interpret key differences by homology modelling. In this paper we used predictions that two residues were primarily responsible for specificity difference between LeuDH and PheDH. Single and double mutations validated the prediction
Featured Image
Read the Original
This page is a summary of: Alteration in relative activities of phenylalanine dehydrogenase towards different substrates by site‐directed mutagenesis, FEBS Letters, August 1995, Wiley,
DOI: 10.1016/0014-5793(95)00804-i.
You can read the full text:
Contributors
The following have contributed to this page
