What is it about?
Our recently published review, “Deciphering the Anti-Aging Potential of Probiotics: A Narrative Review on Gerobiotics,” explores the emerging role of probiotics as modulators of aging and age-related health. We summarize current evidence on how specific probiotic strains—termed gerobiotics—influence gut microbiota composition, reduce oxidative stress, modulate inflammation, and enhance metabolic and immune functions, all of which are critical for healthy aging. The article highlights mechanistic insights, potential clinical applications, and future research directions, positioning probiotics as promising candidates for interventions targeting longevity and age-associated disorders.
Featured Image
Photo by Nastya Dulhiier on Unsplash
Why is it important?
Aging is associated with chronic inflammation, oxidative stress, and changes in gut microbiota, which contribute to age-related diseases and reduced quality of life. Understanding the role of probiotics (gerobiotics) in modulating these processes offers a natural, accessible approach to promoting healthy aging, improving metabolic and immune functions, and potentially delaying age-related disorders. This review provides a foundation for future research and the development of targeted probiotic interventions to support longevity and well-being.
Perspectives
From my perspective, probiotics represent a promising, yet underexplored, avenue for promoting healthy aging. By focusing on gerobiotics, we can move beyond general gut health to targeted interventions that modulate inflammation, oxidative stress, and microbiota composition in aging individuals. I believe that integrating mechanistic insights with clinical applications will pave the way for personalized probiotic therapies that enhance longevity, quality of life, and overall well-being.
Dr. Abrar Hussain
University of Karachi
Read the Original
This page is a summary of: Deciphering the anti-aging potential of probiotics: A narrative review on gerobiotics, The Microbe, December 2025, Elsevier,
DOI: 10.1016/j.microb.2025.100607.
You can read the full text:
Resources
Gerobiotics: Life Enhancing Probiotics
My lecture
The anti-aging properties of probiotics
Young Scientists’ Conference on Multidisciplinary Research - 2023At: Young Scientists’ Association (NIFS-YSA), National Institute of Fundamental Studies, Hanthana Road, Kandy, Sri Lanka
The anti-aging effect of probiotics
Genetics Week Virtual Event Series 2023, Poster
Contributors
The following have contributed to this page
