What is it about?
Pityriasis rosea (PR) is a self-limited disease with exanthematous papulosquamous rashes mostly associated with the reactivation of human herpesvirus (HHV)-6 or HHV-7. PR-like eruptions, which occur along with peripheral eosinophilia, interface dermatitis, and eosinophils on histopathology, may result from medications or vaccinations. Previously, PR-like eruptions had been noted following immunisation for influenza or other vaccines. During this pandemic, acute COVID-19 infection has been related to PR or PR-like eruptions in several cases. Various COVID-19 vaccines associated with PR-like eruptions were rarely reported.
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Why is it important?
We report a case of cutaneous PR-like eruptions with eosinophils in the histopathological findings following COVID-19 mRNA-1273 vaccine injection. Further studies on direct tissue and serological examination for evidence of HHV-6 and HHV-7 reactivation are mandatory to confirm the causative link between PR-like eruptions and COVID-19 vaccination
Read the Original
This page is a summary of: Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review, Journal of the Formosan Medical Association, May 2022, Elsevier,
DOI: 10.1016/j.jfma.2021.12.028.
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