What is it about?

This review looks at how diabetes affects the surface of the eye, not just the back of the eye (retina) that doctors usually focus on. It covers recent research on eye surface problems in diabetics, including nerve issues, dry eyes, and changes to the cornea (the clear front part of the eye).

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Why is it important?

Understanding how diabetes affects the eye surface is important because: It can lead to serious vision problems that aren't as well-known as retina issues Eye surface changes might help doctors spot or manage other diabetes complications It could lead to new ways to diagnose and treat diabetes-related eye problems

Perspectives

Here's what the review covers: Eye surface problems in people who are pre-diabetic (not yet fully diabetic) Differences between eye problems in human diabetics and animal models of diabetes New ways scientists are studying these eye problems in the lab The latest methods for spotting and treating diabetes-related eye surface issues A special microscope technique (in vivo confocal microscopy) that can look closely at the cornea Exciting new research directions, like using protein analysis technology to diagnose and manage these eye problems This review is like opening a new chapter in the book of diabetes and eye health. While most people know diabetes can affect the back of the eye, this shows that the front of the eye needs attention too. It's exciting because it might give doctors new ways to help diabetic patients: They might be able to catch diabetes complications earlier There could be new treatments for eye surface problems The eye surface might even provide clues about what's happening in the rest of the body By bringing attention to this less-studied area, the review suggests that taking care of the whole eye - not just the retina - is crucial for people with diabetes. It's a reminder that in medicine, sometimes looking at things from a new angle can lead to important discoveries and better care for patients.

Prof Louis Tong
National University of Singapore

Read the Original

This page is a summary of: The ocular surface and diabetes, the other 21st Century epidemic, Experimental Eye Research, May 2022, Elsevier,
DOI: 10.1016/j.exer.2022.109099.
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