What is it about?
Calcium in both extracellular and intracellular condition can hinder the adipocyte differentiation. In this study, calcium is transferred into the stem cells by a specific ionophore during the early stage of adipogenesis and the consequences are evaluated.
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Why is it important?
The fact that calcium is always consider to be an anti-obesity element is well-known. Mechanisms such as saponification, inhibiting lipogenesis and stimulating lipolysis. In this study, the differentiation of stem cells is investigated as these cells are a potent resource of newly formed adipocyte that are composed during the obesity.
Perspectives
Although for me the calcium is always a unique element in metabolism, this work was brought me new insights to base a new protocol for neuronal differentiation of mesenchymal stem cells.
Dr Farjam Goudarzi
Hamadan University of Medical Sciences
Read the Original
This page is a summary of: The Role of Calcium in Differentiation of Human Adipose-Derived Stem Cells to Adipocytes, Molecular Biotechnology, February 2018, Springer Science + Business Media,
DOI: 10.1007/s12033-018-0071-x.
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