What is it about?
Our preclinical study demonstrated a successful myocardial infarction induction in all animals, without any reported adverse effect related to the intrapericardial administration of CDCs or EV-CDCs.
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Why is it important?
Intrapericardially administered EV-CDCs have an immunomodulatory effect on monocyte polarization,
Perspectives
EV-CDCs counteract an unbalanced inflammatory reaction in the acute phase of myocardial infarction.
Dr Javier G Casado
University of Extremadura
Read the Original
This page is a summary of: Author Correction: The Intrapericardial Delivery of Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization during the Acute Phase of Porcine Myocardial Infarction, Stem Cell Reviews and Reports, February 2020, Springer Science + Business Media,
DOI: 10.1007/s12015-020-09962-z.
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