What is it about?
Flucytosine-β-cyclodextrin and hydroxypropyl β-cyclodextrin water soluble inclusion complex were prepared by freeze drying method in distilled water. The formation of inclusion complex has been studied and fully described in our previous work
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Why is it important?
As expected the new inclusion complexes presents a semnificative increase of the antifungal activity, illustrated by the reduction of the minimal inhibitory concentrations for 50 and 90% of the tested strains decreased.
Perspectives
These results recommend the described conjugates as future promising therapeutic agents.
Prof. Liviu Dan MIRON
Ion Ionescu de la Brad Iasi University of Life Sciences
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This page is a summary of: Water soluble 5 FC complexes, preliminary pharmacological studies, Journal of Inclusion Phenomena and Macrocyclic Chemistry, May 2009, Springer Science + Business Media,
DOI: 10.1007/s10847-009-9594-x.
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