What is it about?
Zinc oxide (ZnO) is considered as a potential antimicrobial agent. This work aims to investigate the properties of ZnO and Mn-doped ZnO (1% and 5%) fabricated using aqueous leaf extract of Melastoma malabathricum via green synthesis and its antibacterial activities. The synthesized ZnO and Mn-doped ZnO were characterized using different techniques such as powder X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy and UV–Vis diffuse reflectance spectroscopy. The synthesized ZnO and Mn-doped ZnO were tested for its antibacterial properties on two Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa, and two Gram-positive bacteria: Bacillus subtilis and Staphylococcus aureus. The results showed positive antibacterial effects for B. subtilis and S. aureus only. Among the three materials tested, 1% Mn-doped ZnO exhibited the highest antibacterial activity for B. subtilis with the minimum inhibitory concentration being 50 mg/mL.
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Why is it important?
Zinc oxide (ZnO) is considered as a potential antimicrobial agent. This work aims to investigate the properties of ZnO and Mn-doped ZnO (1% and 5%) fabricated using aqueous leaf extract of Melastoma malabathricum via green synthesis and its antibacterial activities. The synthesized ZnO and Mn-doped ZnO were characterized using different techniques such as powder X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy and UV–Vis diffuse reflectance spectroscopy. The synthesized ZnO and Mn-doped ZnO were tested for its antibacterial properties on two Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa, and two Gram-positive bacteria: Bacillus subtilis and Staphylococcus aureus. The results showed positive antibacterial effects for B. subtilis and S. aureus only. Among the three materials tested, 1% Mn-doped ZnO exhibited the highest antibacterial activity for B. subtilis with the minimum inhibitory concentration being 50 mg/mL.
Perspectives
Zinc oxide (ZnO) is considered as a potential antimicrobial agent. This work aims to investigate the properties of ZnO and Mn-doped ZnO (1% and 5%) fabricated using aqueous leaf extract of Melastoma malabathricum via green synthesis and its antibacterial activities. The synthesized ZnO and Mn-doped ZnO were characterized using different techniques such as powder X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy and UV–Vis diffuse reflectance spectroscopy. The synthesized ZnO and Mn-doped ZnO were tested for its antibacterial properties on two Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa, and two Gram-positive bacteria: Bacillus subtilis and Staphylococcus aureus. The results showed positive antibacterial effects for B. subtilis and S. aureus only. Among the three materials tested, 1% Mn-doped ZnO exhibited the highest antibacterial activity for B. subtilis with the minimum inhibitory concentration being 50 mg/mL.
Professor Mohammad Mansoob Khan
Universiti Brunei Darussalam
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This page is a summary of: Antibacterial activities of zinc oxide and Mn-doped zinc oxide synthesized using Melastoma malabathricum (L.) leaf extract, Bioprocess and Biosystems Engineering, April 2020, Springer Science + Business Media,
DOI: 10.1007/s00449-020-02343-3.
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