What is it about?
The article reviews the function of the TRPML2 protein in immune cells, and how the TRPML2 protein could be used to compensate for the missing TRPML1 protein in Mucolipidosis type IV
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Why is it important?
Many intracellular pathway that activates the immune system remains unknown, and the knowledge on TRPML2 function could help scientists dissect the pathways further.
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This page is a summary of: The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function, Pflügers Archiv - European Journal of Physiology, September 2015, Springer Science + Business Media,
DOI: 10.1007/s00424-015-1732-2.
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