What is it about?

The management of acute gout in the hospital setting may be challenging since most patients are elderly with multiple unstable comorbidities. However, there are no prospective clinical trials for hospitalized patients with gout to guide optimal management. Evidence indicates that steroids or adrenocorticotropic hormone (ACTH) may be effective and safe therapeutic options for these patients. This study aimed at directly comparing the efficacy and safety of ACTH vs betamethasone for the treatment of gout in hospitalized patients. This is the first prospective clinical trial for hospitalized patients with gout. We designed a randomized, open label study to assess the efficacy and safety of a single intramuscular injection of either ACTH or betamethasone in hospitalized patients with acute gout.

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Why is it important?

This is the first prospective clinical trial for hospitalized patients with gout.

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This page is a summary of: ACTH vs steroids for the treatment of acute gout in hospitalized patients: a randomized, open label, comparative study, Rheumatology International, April 2022, Springer Science + Business Media,
DOI: 10.1007/s00296-022-05128-x.
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