What is it about?

The E. coli bacteria was genetically modified to improve the production of a specific type of DNA molecules. These so-called «plasmids» can be used to transfer genetic material to living cells and tissues with the goal of treating or preventing diseases.

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Why is it important?

The ability to produce large amounts of plasmids at a low cost will make it possible to develop affordable, gene based therapeutics and vaccines.

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This page is a summary of: De novo creation of MG1655-derived E. coli strains specifically designed for plasmid DNA production, Applied Microbiology and Biotechnology, August 2012, Springer Science + Business Media,
DOI: 10.1007/s00253-012-4308-5.
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