What is it about?

Plants respond to harsh environmental conditions by altering their gene expression patterns. This process relies on regulatory proteins, transcription factors (TFs) and RNA-binding proteins (RBPs) being major regulatory proteins. This work aimed at identifying dominant TFs and RBPs influencing other regulatory proteins, in response to salinity, cold, UV radiation, wounding, and drought stresses.

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Why is it important?

In light of climate change and adverse environmental conditions, it might be useful to explore genetic engineering approaches to generate stress-resilient plant varieties.

Perspectives

Most studies to date have focused TFs or RBPs to understand regulatory basis of gene expression changes in response to environmental stresses. This study on the contrary aimed at identifying dominant regulatory proteins that could affect other TFs and RBPs and hence cause wide-spread downstream gene expression changes in response to multiple stress conditions.

Dr Nishanth M J
St Joseph's University

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This page is a summary of: Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana, Journal of Applied Genetics, February 2024, Springer Science + Business Media,
DOI: 10.1007/s13353-024-00837-4.
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