What is it about?

Adult hippocampal neurogenesis (AHN; the formation of new neurons in hippocampus) is known to be enhanced by physical exercise. However, the molecular processes underlying this effect are not well-understood. This study aimed at identifying RBPs potentially influencing exercise-induced AHN, using computational tools.

Featured Image

Why is it important?

AHN has potential implications in the maintenance of brain health. Hence, understanding the biology of this process would be of fundamental and clinical importance.

Perspectives

RBPs have emerged as major regulators of multiple molecular and cellular processes. However, their involvement in fine-tuning gene expression patterns underlying AHN, especially in the context of exercise was is yet to be understood. The present work serves as a potential foundation in this regard.

Dr Nishanth M J
St Joseph's University

Read the Original

This page is a summary of: Global Exploration of RNA-Binding Proteins in Exercise-Induced Adult Hippocampal Neurogenesis: A Transcriptome Meta-analysis and Computational Study, Biochemical Genetics, May 2022, Springer Science + Business Media,
DOI: 10.1007/s10528-022-10230-7.
You can read the full text:

Read

Contributors

The following have contributed to this page