Mutational analysis of the thermostable arginine repressor from Bacillus stearothermophilus: dissecting residues involved in DNA binding properties

What is it about?

Site-directed mutagenesis has been used to substitute distinct amino acids located in DNA-binding and oligomerization domains of ArgR repressor of Bacillus stearothermophilus. The data provide new information to explain the mechanism of repressor-operator DNA recognition in thermophilic bacteria.

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