What is it about?

Cytolysis induced by stored human milk was further characterized, using rabbit red blood cells as targets, to determine the contribution of other components, particularly the complement system.

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Why is it important?

Human milk stored over some period in vitro possesses certain cytotoxic properties, which require further studies.

Perspectives

Cytolysis by stored human breast milk was found to be temperature dependent, greatly enhanced by low concentrations of magnesium and calcium ions, but inhibited by moderate to excessive amounts of calcium ions, and by heating at 56°C.

Dr Michael O Ogundele
Mid Cheshire Hospitals NHS Foundation Trust Postgraduate Medical Centre

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This page is a summary of: CYTOTOXICITY BY STORED HUMAN BREAST-MILK: POSSIBLE CONTRIBUTION OF COMPLEMENT SYSTEM, Cell Biology International, August 1999, Wiley,
DOI: 10.1006/cbir.1999.0425.
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