Prenatal diagnosis of total and partial anomalous pulmonary venous connection: multicenter cohort study and meta-analysis

What is it about?

A literature review and analysis of published data confirmed that isolated TAPVC is associated with other cardiac and extra-cardiac lesions in 28% and 18% of cases. The diagnosis in the fetus is based upon three major sonographic findings (ventricular disproportion, increased area behind the LA and the recognition of the vertical vein) and direct evidence on color doppler of abnormal venous drainage. Outcome is favourable in < 50% of the cases, when TAPVC is found in prenatal life.

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