What is it about?

This article describes the toxicological test platform in C. elegans (a soil nematode) and 3T3-L1 normal murine cells

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Why is it important?

This platform methodology will be of great interest to both environmental engineers who concern the environmental destruction of xenobiotics and investigators who working on the development of new anticancer agents with less side effects.

Perspectives

We want to make safer topoisomerase inhibitors (anticancer agents) both to human beings and soil worms.

Dr. Kyungsu Kang
Korea Institute of Science and Technology

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This page is a summary of: Toxicological evaluation of the topoisomerase inhibitor, etoposide, in the model animalCaenorhabditis elegansand 3T3-L1 normal murine cells, Environmental Toxicology, February 2017, Wiley,
DOI: 10.1002/tox.22406.
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