What is it about?
this work is about the determination of vildagliptin using HPLC and TLC densitometry in presence of L-proline
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Why is it important?
separation of vildagliptin in presence of L-proline is not published before and it was challenging to separate an amino acid with an active constituent (vildagliptin). The presented work can benefit manufacturer to detect the presence of L-poline after synthesis of vildagliptin
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This page is a summary of: Chromatographic separation of vildagliptin and l-
proline as in-process impurity with the application of Youden's test and statistical analysis to test the robustness of the HPLC method, Separation Science Plus, May 2018, Wiley,
DOI: 10.1002/sscp.201800005.
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