What is it about?
In this publication, spherical core-shell polymeric micro-particles [poly(vinyl acetate) core/ poly(vinyl alcohol) shell] are synthesized and the morphological and molecular modifications during shell formation are detailed investigated.
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Why is it important?
Polymeric particles are widely used in medicine. As example, these particles can be used in transarterial vascular embolization and chemoembolization procedures. However, precise control over the morphology, physical, and chemical properties of such particles are essential for the success of the medical procedure. In this study, we show that during the synthesis of such particles, while the morphology of the particles are not affected, changes on size and molar mass properties are usually observed.
Perspectives
Although the modification of poly(vinyl acetate) in poly(vinyl alcohol) has been extensively reported, there are still lack of informations regarding this particular modification in structured spherical particles. For this reason, in this work we tried to make relationships between the modification reaction and the final properties of the core-shell particles (morphology, size, molar mass, and thermal behavior) using a statistical design.
Dr Marco Oliveira
Universidade Federal do Rio Grande do Sul
Read the Original
This page is a summary of: Synthesis of spherical core-shell poly(vinyl acetate)/poly(vinyl alcohol) particles for use in vascular embolization: Study of morphological and molecular modifications during shell formation, Polymer Engineering & Science, June 2015, Wiley,
DOI: 10.1002/pen.24109.
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