Effect of obesity on telomere length: Systematic review and meta-analysis

What is it about?

With our review we noted a trend toward a negative association between telomere length and obesity, particularly in abdominal body region, but did not find longitidinais studies that could establish a causal relationship.

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Why is it important?

Telomere shortening is a natural aging process that can be accelerated by oxidative stress and inflammation, or attenuated by factors associated with good health. Different life conditions have a negative effect on telomere length, which is modulated by oxidative stress, inflammation and lifestyle variables. Obesity increases the risk of many physical and mental conditions. With our review we noted a trend toward a negative association between telomere length and obesity, particularly in abdominal body region, but did not find longitidinais studies that could establish a causal relationship.