What is it about?

We assessed a combination of three drugs, namely Daclatasvir, asunaprevir, and beclabuvir, in treatment of Hepatitis C virus (HCV) genotype 1, which is the most prevalent HCV type globally and responsible for 60% of infection.

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Why is it important?

This analysis showed high response rates in HCV genotype 1-infected patients treated with the combination irrespective of ribavirin use, prior interferon-based therapy, or restriction on non-cirrhotic patients, IL28B genotype, or baseline resistance-associated variants.

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This page is a summary of: Beclabuvir in combination with asunaprevir and daclatasvir for hepatitis C virus genotype 1 infection: A systematic review and meta-analysis, Journal of Medical Virology, February 2018, Wiley,
DOI: 10.1002/jmv.24947.
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